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Assembly and Replication of HIV-1 in T Cells with Low Levels of Phosphatidylinositol-(4,5)-Bisphosphate

HIV-1 Gag assembles into virus particles predominantly at the plasma membrane (PM). Previously, we observed that phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P(2)] is essential for Gag binding to the plasma membrane and virus release in HeLa cells. In the current study, we found that PI(4,5)P(2)...

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Detalhes bibliográficos
Main Authors: Monde, Kazuaki, Chukkapalli, Vineela, Ono, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067840/
https://ncbi.nlm.nih.gov/pubmed/21270152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02266-10
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