The Essential Human Cytomegalovirus Gene UL52 Is Required for Cleavage-Packaging of the Viral Genome

Replication of human cytomegalovirus (HCMV) produces large DNA concatemers of head-to-tail-linked viral genomes that upon packaging into capsids are cut into unit-length genomes. The mechanisms underlying cleavage-packaging and the subsequent steps prior to nuclear egress of DNA-filled capsids are i...

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Detalhes bibliográficos
Main Authors: Borst, Eva Maria, Wagner, Karen, Binz, Anne, Sodeik, Beate, Messerle, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258901/
https://ncbi.nlm.nih.gov/pubmed/18077717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01967-07
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