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Antigen Delivered by Anthrax Lethal Toxin Induces the Development of Memory CD8(+) T Cells That Can Be Rapidly Boosted and Display Effector Functions

Memory CD8(+) T cells are essential for protective immunity against many intracellular pathogens; therefore, stimulation of this population of cells is an important goal of vaccination. We have previously shown that a detoxified derivative of Bacillus anthracis anthrax lethal toxin (LT) can deliver...

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Detalhes bibliográficos
Main Authors: Shaw, Christine A., Starnbach, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258811/
https://ncbi.nlm.nih.gov/pubmed/18086810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01208-07
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