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The Wnt Pool of Glycogen Synthase Kinase 3β Is Critical for Trophic-Deprivation-Induced Neuronal Death

Glycogen synthase kinase 3 (GSK-3) is implicated in neuronal death through a causal role, and precise mechanisms have not been unambiguously defined. We show that short hairpin RNA (shRNA) knockdown of GSK-3β, but not GSK-3α, protects cerebellar granule neurons from trophic-deprivation-induced death...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hongisto, Vesa, Vainio, Jenni C., Thompson, Róisín, Courtney, Michael J., Coffey, Eleanor T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258793/
https://ncbi.nlm.nih.gov/pubmed/18195042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02227-06
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