Lithium Blocks the c-Jun Stress Response and Protects Neurons via Its Action on Glycogen Synthase Kinase 3

Lithium has been used as an effective mood-stabilizing drug for the treatment of manic episodes and depression for 50 years. More recently, lithium has been found to protect neurons from death induced by a wide array of neurotoxic insults. However, the molecular basis for the prophylactic effects of...

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Detalhes bibliográficos
Main Authors: Hongisto, Vesa, Smeds, Nina, Brecht, Stephan, Herdegen, Thomas, Courtney, Michael J., Coffey, Eleanor T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC180950/
https://ncbi.nlm.nih.gov/pubmed/12917327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.17.6027-6036.2003
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