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Mitochondrial Iba57p Is Required for Fe/S Cluster Formation on Aconitase and Activation of Radical SAM Enzymes

A genome-wide screen for Saccharomyces cerevisiae iron-sulfur (Fe/S) cluster assembly mutants identified the gene IBA57. The encoded protein Iba57p is located in the mitochondrial matrix and is essential for mitochondrial DNA maintenance. The growth phenotypes of an iba57Δ mutant and extensive funct...

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Detalles Bibliográficos
Main Authors: Gelling, Cristy, Dawes, Ian W., Richhardt, Nadine, Lill, Roland, Mühlenhoff, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258791/
https://ncbi.nlm.nih.gov/pubmed/18086897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01963-07
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