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An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1

Depletion of the mitochondrial matrix protein frataxin is the molecular cause of the neurodegenerative disease Friedreich ataxia. The function of frataxin is unclear, although recent studies have suggested a function of frataxin (yeast Yfh1) in iron/sulphur (Fe/S) protein biogenesis. Here, we show t...

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Autors principals: Gerber, Jana, Mühlenhoff, Ulrich, Lill, Roland
Format: Artigo
Idioma:Inglês
Publicat: 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326356/
https://ncbi.nlm.nih.gov/pubmed/12947415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor918
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