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Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally

Posttranslational modifications play important roles in regulating protein structure and function. Histone deacetylase 6 (HDAC6) is a mostly cytoplasmic class II HDAC, which has a unique structure with two catalytic domains and a domain binding ubiquitin with high affinity. This enzyme was recently...

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Detalhes bibliográficos
Main Authors: Zhang, Yu, Kwon, SoHee, Yamaguchi, Teppei, Cubizolles, Fabien, Rousseaux, Sophie, Kneissel, Michaela, Cao, Chun, Li, Na, Cheng, Hwei-Ling, Chua, Katrin, Lombard, David, Mizeracki, Adam, Matthias, Gabriele, Alt, Frederick W., Khochbin, Saadi, Matthias, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258784/
https://ncbi.nlm.nih.gov/pubmed/18180281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01154-06
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