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Protein Engineering of Toluene Monooxygenases for Synthesis of Chiral Sulfoxides
Enantiopure sulfoxides are valuable asymmetric starting materials and are important chiral auxiliaries in organic synthesis. Toluene monooxygenases (TMOs) have been shown previously to catalyze regioselective hydroxylation of substituted benzenes and phenols. Here we show that TMOs are also capable...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2258606/ https://ncbi.nlm.nih.gov/pubmed/18192418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01849-07 |
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