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Protein Engineering of Toluene Monooxygenases for Synthesis of Chiral Sulfoxides

Enantiopure sulfoxides are valuable asymmetric starting materials and are important chiral auxiliaries in organic synthesis. Toluene monooxygenases (TMOs) have been shown previously to catalyze regioselective hydroxylation of substituted benzenes and phenols. Here we show that TMOs are also capable...

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Bibliografiset tiedot
Päätekijät: Feingersch, Roi, Shainsky, Janna, Wood, Thomas K., Fishman, Ayelet
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2008
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258606/
https://ncbi.nlm.nih.gov/pubmed/18192418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01849-07
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