Assessment of Serum (1→3)-β-d-Glucan Concentration as a Measure of Disease Burden in a Murine Model of Invasive Pulmonary Aspergillosis

Serum (1→3)-β-d-glucan concentrations were serially measured in the presence and absence of antifungal therapy in a murine model of invasive pulmonary aspergillosis. Serum (1→3)-β-d-glucan was detected early during the course of infection, and reductions in this biomarker were associated with improv...

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Bibliographic Details
Main Authors: Wiederhold, Nathan P., Najvar, Laura K., Vallor, Ana C., Kirkpatrick, William R., Bocanegra, Rosie, Molina, Destiny, Olivo, Marcos, Graybill, John R., Patterson, Thomas F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258522/
https://ncbi.nlm.nih.gov/pubmed/18160526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01425-07
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