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IL-9 and IL-13 Induce Mucous Cell Metaplasia That Is Reduced by IFN-γ in a Bax-Mediated Pathway

One of the major aspects of airway remodeling in asthma is the development of mucous cell metaplasia (MCM). The role of cytokines in the generation and resolution of MCM has been studied in mice and in isolated airway epithelial cells in culture. However, studies using organ cultures that keep the t...

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Detalles Bibliográficos
Main Authors: Xiang, Jialing, Rir-Sim-Ah, Jules, Tesfaigzi, Yohannes
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258450/
https://ncbi.nlm.nih.gov/pubmed/17901408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0078OC
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