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Ozone, Oxidant Defense Genes, and Risk of Asthma during Adolescence

Rationale: Although oxidative stress is a cardinal feature of asthma, the roles of oxidant air pollutants and antioxidant genes heme oxygenase 1 (HMOX-1), catalase (CAT), and manganese superoxide dismutase (MNSOD) in asthma pathogenesis have yet to be determined. Objectives: We hypothesized that the...

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Main Authors: Islam, Talat, McConnell, Rob, Gauderman, W. James, Avol, Ed, Peters, John M., Gilliland, Frank D.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258440/
https://ncbi.nlm.nih.gov/pubmed/18048809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200706-863OC
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