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Positive Feedback and Noise Activate the Stringent Response Regulator Rel in Mycobacteria

Phenotypic heterogeneity in an isogenic, microbial population enables a subset of the population to persist under stress. In mycobacteria, stresses like nutrient and oxygen deprivation activate the stress response pathway involving the two-component system MprAB and the sigma factor, SigE. SigE in t...

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Detalhes bibliográficos
Main Authors: Sureka, Kamakshi, Ghosh, Bhaswar, Dasgupta, Arunava, Basu, Joyoti, Kundu, Manikuntala, Bose, Indrani
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258413/
https://ncbi.nlm.nih.gov/pubmed/18335046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001771
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