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Insertion Signal Sequence Fused to Minimal Peptides Elicits Specific CD8(+) T-Cell Responses and Prolongs Survival of Thymoma-bearing Mice

CD8(+) T-lymphocytes (T(CD8+)) recognize minimal peptides of 8–10 residues which are the products of intracellularly processed proteins and are presented at the cell surface by major histocompatibility complex class I molecules. An important step in this process is the translocation of processed pro...

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Autori principali: Minev, Boris R., McFarland, Barbra J., Spiess, Paul J., Rosenberg, Steven A., Restifo, Nicholas P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254935/
https://ncbi.nlm.nih.gov/pubmed/7518351
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