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Rapid Mix Flow Cytometry Measurements of Subsecond Regulation of G Protein-Coupled Receptor Ternary Complex Dynamics by Guanine Nucleotides

We have used rapid mix flow cytometry to analyze the early subsecond dynamics of the disassembly of ternary complexes of G-protein coupled receptors (GPCRs) immobilized on beads to examine individual steps associated with guanine nucleotide activation. Our earlier studies suggested that the slow dis...

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Detalhes bibliográficos
Main Authors: Wu, Yang, Buranda, Tione, Simons, Peter C., Lopez, Gabriel P., McIntire, William E., Garrison, James C., Prossnitz, Eric R., Sklar, Larry A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254650/
https://ncbi.nlm.nih.gov/pubmed/17904091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.08.011
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