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Peroxynitrite activates ERK via Raf-1 and MEK, independently from EGF receptor and p21(Ras) in H9C2 cardiomyocytes

Peroxynitrite is a potent oxidant and nitrating species proposed as a direct effector of myocardial damage in a wide range of cardiac diseases. Whether peroxynitrite also acts indirectly, by modulating cell signal transduction pathways in the myocardium, has not been investigated. Here, we examined...

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Detalhes bibliográficos
Main Authors: Pesse, B., Levrand, S., Feihl, F., Waeber, B., Gavillet, B., Pacher, P., Liaudet, L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254583/
https://ncbi.nlm.nih.gov/pubmed/15850570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2005.02.020
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