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Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor
Semaphorin 3A (Sema3A), a known inhibitor of axonal sprouting, also alters vascular patterning. Here we show that Sema3A selectively interferes with VEGF- but not bFGF-induced angiogenesis in vivo. Consistent with this, Sema3A disrupted VEGF- but not bFGF-mediated endothelial cell signaling to FAK a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254547/ https://ncbi.nlm.nih.gov/pubmed/18180379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-08-110205 |
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