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Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

Autophagy is an evolutionally conserved “self-eating” process. Although the genes essential for autophagy (termed Atg) have been identified in yeast, the molecular mechanism of how these Atg proteins control autophagosome formation in mammalian cells remains to be elucidated. Here, we demonstrate th...

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Détails bibliographiques
Auteurs principaux: Takahashi, Yoshinori, Coppola, Domenico, Matsushita, Norimasa, Cualing, Hernani D., Sun, Mei, Sato, Yuya, Liang, Chengyu, Jung, Jae U., Cheng, Jin Q., Mulé, James J., Pledger, W. Jack, Wang, Hong-Gang
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254521/
https://ncbi.nlm.nih.gov/pubmed/17891140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1634
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