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Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

Autophagy is an evolutionally conserved “self-eating” process. Although the genes essential for autophagy (termed Atg) have been identified in yeast, the molecular mechanism of how these Atg proteins control autophagosome formation in mammalian cells remains to be elucidated. Here, we demonstrate th...

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Autors principals: Takahashi, Yoshinori, Coppola, Domenico, Matsushita, Norimasa, Cualing, Hernani D., Sun, Mei, Sato, Yuya, Liang, Chengyu, Jung, Jae U., Cheng, Jin Q., Mulé, James J., Pledger, W. Jack, Wang, Hong-Gang
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254521/
https://ncbi.nlm.nih.gov/pubmed/17891140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1634
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