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Estimating effects of rare haplotypes on failure time using a penalized Cox proportional hazards regression model
BACKGROUND: This paper describes a likelihood approach to model the relation between failure time and haplotypes in studies with unrelated individuals where haplotype phase is unknown, while dealing with the problem of unstable estimates due to rare haplotypes by considering a penalized log-likeliho...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254440/ https://ncbi.nlm.nih.gov/pubmed/18221501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-9-9 |
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