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Estimating effects of rare haplotypes on failure time using a penalized Cox proportional hazards regression model

BACKGROUND: This paper describes a likelihood approach to model the relation between failure time and haplotypes in studies with unrelated individuals where haplotype phase is unknown, while dealing with the problem of unstable estimates due to rare haplotypes by considering a penalized log-likeliho...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Souverein, Olga W, Zwinderman, Aeilko H, Jukema, J Wouter, Tanck, Michael WT
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254440/
https://ncbi.nlm.nih.gov/pubmed/18221501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-9-9
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