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A direct repeat of E-box-like elements is required for cell-autonomous circadian rhythm of clock genes
BACKGROUND: The circadian expression of the mammalian clock genes is based on transcriptional feedback loops. Two basic helix-loop-helix (bHLH) PAS (for Period-Arnt-Sim) domain-containing transcriptional activators, CLOCK and BMAL1, are known to regulate gene expression by interacting with a promote...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254435/ https://ncbi.nlm.nih.gov/pubmed/18177499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-1 |
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