Dynamic regulation of PGC-1α localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response

There is increasing evidence that longevity and stress resistance are connected, but the mechanism is unclear. We report that mitochondria are regulated in response to oxidative stress and calorie restriction through a shared mechanism involving peroxisome proliferator-activated receptor-γ co-activa...

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Detalhes bibliográficos
Main Authors: Anderson, Rozalyn M, Barger, Jamie L, Edwards, Michael G, Braun, Kristina H, O’Connor, Clare E, Prolla, Tomas A, Weindruch, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253697/
https://ncbi.nlm.nih.gov/pubmed/18031569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2007.00357.x
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