Clinical significance of nuclear non-phosphorylated beta-catenin in acute myeloid leukaemia and myelodysplastic syndrome

Wnt signaling activates the canonical pathway and induces the accumulation of non-phosphorylated beta-catenin (NPBC) in the nucleus. Although this pathway plays an important role in the maintenance of haematopoietic stem cells as well as in oncogenesis, the significance of nuclear NPBC remains uncle...

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Autors principals: Xu, Jinglan, Suzuki, Momoko, Niwa, Yousuke, Hiraga, Junji, Nagasaka, Tetsuro, Ito, Masafumi, Nakamura, Shigeo, Tomita, Akihiro, Abe, Akihiro, Kiyoi, Hitoshi, Kinoshita, Tomohiro, Naoe, Tomoki
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2008
Matèries:
Haematological Malignancy
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253692/
https://ncbi.nlm.nih.gov/pubmed/18217891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2007.06914.x
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