Multiple and Additive Functions of ALDH3A1 and ALDH1A1: CATARACT PHENOTYPE AND OCULAR OXIDATIVE DAMAGE IN Aldh3a1(−/−)/Aldh1a1(−/−) KNOCK-OUT MICE

ALDH3A1 (aldehyde dehydrogenase 3A1) is abundant in the mouse cornea but undetectable in the lens, and ALDH1A1 is present at lower (catalytic) levels in the cornea and lens. To test the hypothesis that ALDH3A1 and ALDH1A1 protect the anterior segment of the eye against environmentally induced oxidat...

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Main Authors: Lassen, Natalie, Bateman, J. Bronwyn, Estey, Tia, Kuszak, Jer R., Nees, David W., Piatigorsky, Joram, Duester, Gregg, Day, Brian J., Huang, Jie, Hines, Lisa M., Vasiliou, Vasilis
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253645/
https://ncbi.nlm.nih.gov/pubmed/17567582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M702076200
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