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IdeS: A Bacterial Proteolytic Enzyme with Therapeutic Potential
BACKGROUND: IdeS, a proteinase from Streptococcus pyogenes, cleaves immunoglobulin (Ig)G antibodies with a unique degree of specificity. Pathogenic IgG antibodies constitute an important clinical problem contributing to the pathogenesis of a number of autoimmune conditions and acute transplant rejec...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253494/ https://ncbi.nlm.nih.gov/pubmed/18301769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001692 |
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