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ATP specifically drives refolding of non-native conformations of cytochrome c

An increasing body of evidence ascribes to misfolded forms of cytochrome c (cyt c) a role in pathophysiological events such as apoptosis and disease. Here, we examine the conformational changes induced by lipid binding to horse heart cyt c at pH 7 and study the ability of ATP (and other nucleotides)...

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Detalhes bibliográficos
Main Authors: Sinibaldi, Federica, Mei, Giampiero, Polticelli, Fabio, Piro, M. Cristina, Howes, Barry D., Smulevich, Giulietta, Santucci, Roberto, Ascoli, Franca, Fiorucci, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253445/
https://ncbi.nlm.nih.gov/pubmed/15741329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041069405
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