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Crystal structure of the complex formed between a group I Phospholipase A(2) and a naturally occurring fatty acid at 2.7 Å resolution
This is the first evidence of a naturally bound fatty acid to a group I Phospholipase A(2) (PLA(2)) and also to a PLA(2) with Asp 49. The fatty acid identified as n-tridecanoic acid is observed at the substrate recognition site of PLA(2) hydrophobic channel. The complex was isolated from the venom o...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2005
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253428/ https://ncbi.nlm.nih.gov/pubmed/15659372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041115505 |
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