Crystal structure of the complex formed between a group I Phospholipase A(2) and a naturally occurring fatty acid at 2.7 Å resolution

This is the first evidence of a naturally bound fatty acid to a group I Phospholipase A(2) (PLA(2)) and also to a PLA(2) with Asp 49. The fatty acid identified as n-tridecanoic acid is observed at the substrate recognition site of PLA(2) hydrophobic channel. The complex was isolated from the venom o...

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Main Authors: Singh, Garima, Jasti, Jayasankar, Saravanan, K., Sharma, Sujata, Kaur, Punit, Srinivasan, A., Singh, Tej P.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253428/
https://ncbi.nlm.nih.gov/pubmed/15659372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041115505
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