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Do all backbone polar groups in proteins form hydrogen bonds?

Evidence from proteins and peptides supports the conclusion that intrapeptide hydrogen bonds stabilize the folded form of proteins. Paradoxically, evidence from small molecules supports the opposite conclusion, that intrapeptide hydrogen bonds are less favorable than peptide–water hydrogen bonds. A...

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Autors principals: Fleming, Patrick J., Rose, George D.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253345/
https://ncbi.nlm.nih.gov/pubmed/15937286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051454805
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