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Structural characterization of Lyn-SH3 domain in complex with a herpesviral protein reveals an extended recognition motif that enhances binding affinity

The Src homology 3 (SH3) domain of the Src family kinase Lyn binds to the herpesviral tyrosine kinase interacting protein (Tip) more than one order of magnitude stronger than other closely related members of the Src family. In order to identify the molecular basis for high-affinity binding, the stru...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bauer, Finn, Schweimer, Kristian, Meiselbach, Heike, Hoffmann, Silke, Rösch, Paul, Sticht, Heinrich
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253286/
https://ncbi.nlm.nih.gov/pubmed/16155203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051563605
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