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Arginine-140 and isoleucine-141 determine the 17β-estradiol-binding specificity of the sex-steroid-binding protein (SBP, or SHBG) of human plasma
Arginine-140 and isoleucine-141 were identified as key determinants of 17β-estradiol (E(2)) binding affinity of the sex-steroid-binding protein (SBP, or SHBG) of human plasma. Amino acid residues that differ between human and rabbit SBP sequences were replaced in the human protein and the products t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253199/ https://ncbi.nlm.nih.gov/pubmed/11514672 |
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