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Bioluminescence Imaging Reveals Systemic Dissemination of Herpes Simplex Virus Type 1 in the Absence of Interferon Receptors

Herpes simplex virus type 1 (HSV-1) can produce disseminated, systemic infection in neonates and patients with AIDS or other immunocompromising diseases, resulting in significant morbidity and mortality in spite of antiviral therapy. Components of host immunity that normally limit HSV-1 to localized...

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Autori principali: Luker, Gary D., Prior, Julie L., Song, Jiling, Pica, Christina M., Leib, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC224994/
https://ncbi.nlm.nih.gov/pubmed/14512556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.11082-11093.2003
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