Bioluminescence Imaging Reveals Systemic Dissemination of Herpes Simplex Virus Type 1 in the Absence of Interferon Receptors

Herpes simplex virus type 1 (HSV-1) can produce disseminated, systemic infection in neonates and patients with AIDS or other immunocompromising diseases, resulting in significant morbidity and mortality in spite of antiviral therapy. Components of host immunity that normally limit HSV-1 to localized...

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Detalhes bibliográficos
Main Authors: Luker, Gary D., Prior, Julie L., Song, Jiling, Pica, Christina M., Leib, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC224994/
https://ncbi.nlm.nih.gov/pubmed/14512556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.11082-11093.2003
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