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Understanding thermostability in cytochrome P450 by combinatorial mutagenesis
The cytochromes P450 are an important class of mono-oxygenases involved in xenobiotic metabolism and steroid biosynthesis in a diverse set of life forms. Discovery of CYP-119, a P450 from the archea Sulfolobus solfataricus has provided a means for understanding nature's method of stabilizing th...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
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Cold Spring Harbor Laboratory Press
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2249849/ https://ncbi.nlm.nih.gov/pubmed/11266604 |
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