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Patterns of Intra- and Interhost Nonsynonymous Variation Reveal Strong Purifying Selection in Dengue Virus

Considerable uncertainty surrounds the evolutionary rates of and selection pressures acting on arthropod-borne RNA viruses (arboviruses). In particular, it is unclear why arboviruses such as dengue virus show substantial genetic variation within individual humans and mosquitoes yet low long-term rat...

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Bibliografski detalji
Glavni autor: Holmes, Edward C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC224983/
https://ncbi.nlm.nih.gov/pubmed/14512579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.11296-11298.2003
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