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Domain:domain interactions within Hop, the Hsp70/Hsp90 organizing protein, are required for protein stability and structure

The major heat shock protein (Hsp) chaperones Hsp70 and Hsp90 both bind the co-chaperone Hop (Hsp70/Hsp90 organizing protein), which coordinates Hsp actions in folding protein substrates. Hop contains three tetratricopeptide repeat (TPR) domains that have binding sites for the conserved EEVD C termi...

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Detalles Bibliográficos
Autores principales: Carrigan, Patricia E., Sikkink, Laura A., Smith, David F., Ramirez-Alvarado, Marina
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249773/
https://ncbi.nlm.nih.gov/pubmed/16452615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051810106
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