In Vitro Proteolytic Processing of the MD145 Norovirus ORF1 Nonstructural Polyprotein Yields Stable Precursors and Products Similar to Those Detected in Calicivirus-Infected Cells

The MD145-12 strain (GII/4) is a member of the genus Norovirus in the Caliciviridae and was detected in a patient with acute gastroenteritis in a Maryland nursing home. The open reading frame 1 (ORF1) (encoding the nonstructural polyprotein) was cloned as a consensus sequence into various expression...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Belliot, Gaël, Sosnovtsev, Stanislav V., Mitra, Tanaji, Hammer, Carl, Garfield, Mark, Green, Kim Y.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2003
Matèries:	Replication
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC224964/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14512545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.20.10957-10974.2003
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