Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero
Two B-type cyclins, B1 and B2, have been identified in mammals. Proliferating cells express both cyclins, which bind to and activate p34(cdc2). To test whether the two B-type cyclins have distinct roles, we generated lines of transgenic mice, one lacking cyclin B1 and the other lacking cyclin B2. Cy...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1998
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22491/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539739/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4344 |
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