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Mutation of the arginine finger in the active site of Escherichia coli DbpA abolishes ATPase and helicase activity and confers a dominant slow growth phenotype
Escherichia coli DEAD-box protein A (DbpA) is an ATP-dependent RNA helicase with specificity for 23S ribosomal RNA. Although DbpA has been extensively characterized biochemically, its biological function remains unknown. Previous work has shown that a DbpA deletion strain is viable with little or no...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2008
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2248767/ https://ncbi.nlm.nih.gov/pubmed/17986459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm926 |
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