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Alternative polyadenylation signals and promoters act in concert to control tissue-specific expression of the Opitz Syndrome gene MID1

BACKGROUND: Mutations in the X-linked MID1 gene are responsible for Opitz G/BBB syndrome, a malformation disorder of developing midline structures. Previous Northern blot analyses revealed the existence of at least three MID1 transcripts of differing lengths. RESULTS: Here we show that alternative p...

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Detalhes bibliográficos
Main Authors: Winter, Jennifer, Kunath, Melanie, Roepcke, Stefan, Krause, Sven, Schneider, Rainer, Schweiger, Susann
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248598/
https://ncbi.nlm.nih.gov/pubmed/18005432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-105
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