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Three factors underlying incorrect in silico predictions of essential metabolic genes

BACKGROUND: The indispensability of certain genes in an organism is important for studies of microorganism physiology, antibiotic targeting, and the engineering of minimal genomes. Time and resource intensive genome-wide experimental screens can be conducted to determine which genes are likely essen...

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Detalhes bibliográficos
Main Authors: Becker, Scott A, Palsson, Bernhard O
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248557/
https://ncbi.nlm.nih.gov/pubmed/18248675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-2-14
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