Quantitative Correlation between HLA Class I Allele Expression and Recognition of Melanoma Cells by Antigen-specific Cytotoxic T Lymphocytes

MHC class I antigen expression is necessary for CD8+ T-cell-mediated recognition of tumors. Recently, several mechanisms leading to loss or decreased expression of MHC antigens on the tumor cell surface have been described that may account for tumor escape from immune recognition. It is yet unknown...

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Main Authors: Rivoltini, Licia, Barracchini, Kathleen C., Viggiano, Vincenzo, Kawakami, Yutaka, Smith, Andrew, Mixon, Arnold, Restifo, Nicholas P., Topalian, Suzanne L., Simonis, Toni B., Rosenberg, Steven A., Marincola, Francesco M.
Format: Artigo
Language:Inglês
Published: 1995
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248458/
https://ncbi.nlm.nih.gov/pubmed/7541714
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