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NATURAL VARIATION OF THE EXPRESSION OF HLA AND ENDOGENOUS ANTIGEN MODULATES CTL RECOGNITION IN AN IN VITRO MELANOMA MODEL

Increasing attention has been devoted to elucidating the mechanism of lost or decreased expression of MHC or melanoma-associated antigens (MAAs), which may lead to tumor escape from immune recognition. Loss of expression of HLA class I or MAA has, as an undisputed consequence, loss of recognition by...

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Autors principals: Cormier, Janice N., Panelli, Monica C., Hackett, Julia A., Bettinotti, Maria P., Mixon, Arnold, Wunderlich, John, Parker, Linda L., Restifo, Nicholas P., Ferrone, Soldano, Marincola, Francesco M.
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072935/
https://ncbi.nlm.nih.gov/pubmed/10048982
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