Selective Histocompatibility Leukocyte Antigen (Hla)-A2 Loss Caused by Aberrant Pre-mRNA Splicing in 624mel28 Melanoma Cells

Histocompatibility leukocyte antigen (HLA)-A2 is used as a restricting element to present several melanoma-associated antigen (MAA)-derived peptides to cytotoxic T lymphocytes (CTLs). HLA-A2 antigen is selectively lost in primary melanoma lesions and more frequently in metastases. Only scanty inform...

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Bibliographic Details
Main Authors: Wang, Zhigang, Marincola, Francesco M., Rivoltini, Licia, Parmiani, Giorgio, Ferrone, Soldano
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1999
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195569/
https://ncbi.nlm.nih.gov/pubmed/10432284
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