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Functional Interactions Between Sae2 and the Mre11 Complex

The Mre11 complex functions in double-strand break (DSB) repair, meiotic recombination, and DNA damage checkpoint pathways. Sae2 deficiency has opposing effects on the Mre11 complex. On one hand, it appears to impair Mre11 nuclease function in DNA repair and meiotic DSB processing, and on the other,...

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Detalhes bibliográficos
Main Authors: Kim, Hee-Sook, Vijayakumar, Sangeetha, Reger, Mike, Harrison, Jacob C., Haber, James E., Weil, Clifford, Petrini, John H. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248341/
https://ncbi.nlm.nih.gov/pubmed/18245357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.081331
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