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Excessive complement activation is associated with placental injury in patients with antiphospholipid antibodies

OBJECTIVE: Studies that use a murine model of antiphospholipid syndrome have demonstrated a critical role for complement activation that leads to fetal and placental injury in the presence of antiphospholipid antibodies (APAs). We examined the placentas of patients with APAs to demonstrate a similar...

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Detalhes bibliográficos
Main Authors: Shamonki, Jaime M., Salmon, Jane E., Hyjek, Elizabeth, Baergen, Rebecca N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248299/
https://ncbi.nlm.nih.gov/pubmed/17306667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2006.10.879
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