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Improved polymerase ribozyme efficiency on hydrophobic assemblies

During an early step in the evolution of life, RNA served both as genome and as catalyst, according to the RNA world hypothesis. For self-replication, the RNA organisms must have contained an RNA that catalyzes RNA polymerization. As a first step toward recapitulating an RNA world in the laboratory,...

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Autors principals: Müller, Ulrich F., Bartel, David P.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248263/
https://ncbi.nlm.nih.gov/pubmed/18230767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.494508
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