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Self-excision of the BAC sequences from the recombinant Marek's disease virus genome increases replication and pathogenicity
Cloning of full length genomes of herpesviruses as bacterial artificial chromosomes (BAC) has greatly facilitated the manipulation of the genomes of several herpesviruses to identify the pathogenic determinants. We have previously reported the construction of the BAC clone (pRB-1B5) of the highly on...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2248170/ https://ncbi.nlm.nih.gov/pubmed/18230192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-19 |
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