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Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth

Apurinic endonuclease 1 / redox factor-1 (Ape1/Ref-1 or Ape1) is an essential protein with two distinct functions. It is a DNA repair enzyme in the base excision repair (BER) pathway and a reduction-oxidation (redox) signaling factor maintaining transcription factors in an active reduced state. Our...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Fishel, Melissa L., He, Ying, Reed, April M., Chin-Sinex, Helen, Hutchins, Gary D., Mendonca, Marc S., Kelley, Mark R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2007
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247410/
https://ncbi.nlm.nih.gov/pubmed/17974506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.09.008
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