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Rapid ligand-regulated gating kinetics of single inositol 1,4,5-trisphosphate receptor Ca(2+) release channels

The ubiquitous inositol 1,4,5-trisphosphate receptor (InsP(3)R) intracellular Ca(2+) release channel is engaged by thousands of plasma membrane receptors to generate Ca(2+) signals in all cells. Understanding how complex Ca(2+) signals are generated has been hindered by a lack of information on the...

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Detalhes bibliográficos
Main Authors: Mak, Don-On Daniel, Pearson, John E, Loong, King Pan Campion, Datta, Suman, Fernández-Mongil, Marisabel, Foskett, J Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247393/
https://ncbi.nlm.nih.gov/pubmed/17932510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401087
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